Quick Detail

Introduction

It is a kind of non-ionic surfactant with strong hydrophilicity, has emulsification, diffusion, solubilization, stable function, widely used in pharmaceutical, cosmetic, food, textile and other industries

The product has offodor and faint bitter taste, can keep stable in electrolyte, weak acid and weak base and in strong acid alkali will appears saponification gradually, has certain moisture absorption.

Applications

When the vegetable oil is not suitable for a co-active ingredient carrier material, the polyethylene glycol is the preferred substitute material because the polyethylene glycol is stable and non-perishable. Besides, the injections containing polyethylene glycol are very safe and stable as long as it has been heated to 150 degrees Celsius. In addition, it can blend with PEG with high molecular weight and the mixture has a good solubility and drug compatibility.

Polyethylene glycol 400 is suited to prepare for the soft capsule most. The polyethylene glycol 400 is a liquid and has a broad compatibility with various solvents, so it is a good solvent and solubilizer and is widely used in liquid preparations, such as the oral solution, eye drops and so on.

For example in ice cream, polysorbate is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting. Adding this substance prevents milk proteins from completely coating the fat droplets. This allows them to join together in chains and nets, which hold air in the mixture, and provide a firmer texture that holds its shape as the ice cream melts.

Health and beauty use:Polysorbate 80 is also used as a surfactant in soaps and cosmetics, or a solubilizer such as in a mouthwash. The cosmetic grade of polysorbate 80 may have more impurities than the food grade.

Medical use:Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the manufacture of the popular antiarrhythmic amiodarone. It is also used as an excipient in some European and Canadian influenza vaccines.Influenza vaccines contain 25 μg of polysorbate 80 per dose. It is also used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth. It is also used as an emulsifier in the estrogen-regulating drug Estrasorb.

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