Drostanolone Propionate CAS 58-18-4 17-alpha-Methyl Testosterone Bodybuilding

Drostanolone Propionate CAS 58-18-4 17-alpha-Methyl Testosterone Bodybuilding Steroids

 

 

1, 17-alpha-Methyl Testosterone Quick Details

 

 

Product name	17-alpha-Methyl Testosterone
Other name	17beta-hydroxy-17alpha-methylandrost-4-en-3-one; Mesterone; Andrometh; 17-Methyl Testosterone;  Nu-man; Testoviron;Metandren
CAS register number	58-18-4
EINECS	200-366-3
Molecular formula	C20H30O2
Molecular weight	302. 45
Assay	99%
Appearance	white powder.
Usage	pharmaceutical material, Androgen for testosterone deficiency, replacement therapy can also be used for functional uterine bleeding, aplastic anemia and other diseases treatment. Preparation Products Bolasterone.
Standard	USP
Price	Negotiated
Minimum order quantity	10g
Package:	Exquisite and can according to customers’ requirement
Shipping leading time	Within 24 hours after receiving the payment
Payment options	Western Union, MoneyGram, bank transfer, Bitcoin
Shipping	1) Express delivery with DHL,EMS, Fedex, HKEMS, TNT, UPS(within 5-7days after payment) 2) By sea (large quantity , it will take 30-45days)

 

 

2. Application

 

17alpha-methyl testosterone is used widely as a component of hormone replacement therapy. Previous reports have indicated that contrary to , 17alpha-methyl testosterone is not aromatized. However, 17alpha-methyl testosterone still could affect local estrogen formation by regulating aromatase expression or by inhibiting aromatase action.

 

Both possibilities have important clinical implications. To evaluate the effect of 17alpha-methyl testosterone on the expression and activity of aromatase,  we tested the choriocarcinoma Jar cell line, a cell line that express high levels of P450 aromatase, and the macrophage-like THP-1 cells, which express aromatase only after undergoing differentiation. We found that in both cell lines, 17alpha-methyl testosterone inhibits aromatase activity in a dose-related manner.

 

The curve of inhibition parallels that of letrozole and gives complete inhibition at 10(-4) M 17alpha-methyl testosterone, determined by the tritium release assay. 17alpha-methyl testosterone does not have detectable effects on aromatase RNA and protein expression by Jar cells.

 

Undifferentiated THP-1 cells had no aromatase activity and showed no effect of 17alpha-methyl testosterone, but differentiated THP-1 (macrophage-like) cells had a similar inhibition of aromatase activity by 17alpha-methyl testosterone to that seen in Jar cells. The Lineweaver-Burke plot shows 17alpha-methyl testosterone to be a competitive aromatase inhibitor.

 

Our results show for the first time that 17alpha-methyl testosterone acts as an aromatase inhibitor. These findings are relevant for understanding the effects of 17alpha-methyl testosterone as a component of hormone replacement therapy. 17alpha-methyl testosterone may, as a functional androgen and orally active steroidal inhibitor of endogenous estrogen production, also offer special possibilities for the prevention/treatment of hormone-sensitive cancers.

 

 

3. How to use

17-Methyltestosterone, Take this medication by mouth with or without food,usually 1 to 4 times a day, as directed by your doctor. Dosage is based on your medical condition, testosterone blood levels, and response to treatment.

17-Methyltestosterone, Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.

17-Methyltestosterone, Do not suddenly stop using methyltestosterone if you have been using it regularly for an extended time or if it has been used in high doses. In such cases,your body will no longer make its own testosterone, and withdrawal reactions (such as tiredness,weakness,depression) may occur. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details,and report any withdrawal reactions immediately.

17-Methyltestosterone,Abnormal drug-seeking behavior is possible with this medication, and it is frequently misused for its muscle-enhancing effects. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. Doing so may increase serious side effects (such as increased risk for heart disease,stroke, liver disease, ruptured tendons/ligaments, improper bone development in adolescents). Properly stop the medication when so directed

 

 

4. COA

 

Test Items	Specification	Test Results
Identification	TLC	Positive
	UV spectrum	Positive
	IR spectrum	Positive
Characteristics	White to almost white crystalline powder	Conform
Melting point	162～168℃	152～166℃
Specific optical rotation	+79°～ + 85°	+ 82.5°
Loss on drying	≤ 2.0%	1.1 %
Assay	97～103%	99.08%
Related substances	≤ 1.0%	Pass
Residual solvents(GC)	Acetone ≤ 100ppm	Pass
	Methanol ≤ 100ppm	Pass
	Pyridine ≤ 100ppm	Pass
Conclusion	This batch is complies with USP31

 

 

Our Adavantages

 

1. High quality

 

(1) The purity of our product is tested by our quality department before shipped to our clients.

(2) You can also request for the third party inspections when you confirm your order before shipped.

 

2. Safe and Fast Delivery

 

(1) We work with professional shipping companies to ensure the fast and efficient delivery.

(2) Customs pass rate ≥99%.

(3) We know the best way to ship products to the U.S, Australia, Canada, EU, South America and other regions of the world.

(4) Parcel can be sent out Within 24h after we confirm the payment.

 

3. Quick Response

 

All of your queries will receive response within the day.

 

FAQ

 

1. How about the Delivery time?

We will arrange the delivery within 24 hours after receiving the payment,except for custom products.

 

2. What kind of payments does you support?

T/T, Western Union, PayPal & Cash are accepted.

 

3. Whats the MOQ?

Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.

 

4. Do you charge for the samples?

According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.

 

5. Can you packing according to customers requirements ?

Sure, If you have a request for packing, please tell us, Any good ideas are welcomed.

 

6. Can you tell me your main customers?

Thats our customers privacy, we should protect their information.

At the same time, please rest assured that your information is also safe here.

Well offer you the quotation as soon as possible once receive your inquiry, so don hesitate to contact us.

 

Drostanolone Propionate CAS 58-18-4 17-alpha-Methyl Testosterone Bodybuilding Images