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Home>Products>Muscle Growth Steroids>Anti-Estrogen Powder CAS 302-22-7 Chlormadinone Acetate with fast delivery and

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  • Anti-Estrogen Powder CAS 302-22-7 Chlormadinone Acetate with fast delivery and
  • Anti-Estrogen Powder CAS 302-22-7 Chlormadinone Acetate with fast delivery and

Anti-Estrogen Powder CAS 302-22-7 Chlormadinone Acetate with fast delivery and

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  • CAS:302-22-7

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Wuhan Hezhong Biochemical Manufacturing Co., Ltd.

Wuhan Hezhong Biochemical Manufacturing Co., Ltd.China

  • Wuhan Hezhong Biochemical Manufacturing Co., Ltd.2020-07-10 09:46:19
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Product Details

Appearance: White Crystalline Powder Storage: Cool And Dry Place Assay: Above 99%
Delivery: TNT,DHL,Fedex,EMS,HKEMS,UPS,etc Shipping Method: Air&Sea Transporation,Express Product Name: Chlormadinone Acetate

Product Description

Anti-Estrogen Powder 302-22-7 Chlormadinone Acetate


Quick Detail
Chlormadinone acetate
Product name: Chlormadinone acetate
CAS Registry Number: 302-22-7
Assay: 98%
Molecular Formula: C23H29ClO4
Molecular weight: 404.93
Reference Standard: CP
Appearance: White or slightly yellow crystalline powder

Description:
(1)Chlormadinone acetate (CMA) is a derivative of progesterone (17-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961 and is used as an orally effective progestogen in hormone replacement therapy (HRT), and in combination with ethinyl estradiol (EE) in contraception since 1999.

(2)Chlormadinone acetate has a strong progestogenic effect about one-third higher than that of progesterone and may vary depending on the previous effect of an estrogen, i.e., estrogens may promote the formation of progesterone receptors and proliferation of the endometrium. Like progesterone, it is anti-estrogenic and has no partial androgenic effect (at the doses used for contraception and HRT).

(3)In contrast to progesterone, it has a slight glucocorticoid effect, a pronounced anti-androgenic effect and no anti-mineralocorticoid effect. No pregnancy-maintaining effect of CMA has been demonstrated in humans.

(4)The anti-androgenic effect of CMA is presumed to be the result of both its binding to androgen receptors competitively inhibiting the effect of endogenous testosterone and dihydrotestosterone and the competitive inhibition of 5-reductase. In this respect, dosing of CMA is crucial; agonistic effects are observed when doses are increased from those optimal for an antagonistic effect.

(5)Chlormadinone acetate has a strong anti-gonadotropic effect, through negative feedback on gonadotropin secretion, and has been used for more than 20 years alone for contraception in arterial risk patients. The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.

(6)The more recent application of CMA as an oral contraceptive in combination with EE (Neo Eunomin, Belara) has proven highly successful, with studies reporting excellent contraceptive efficacy, high tolerability and adherence due to a good side effect profile and positive effects on preexisting dysmenorrhea, skin and hair conditions.

Applications:
Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties.

CMA acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase. It suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production.

CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness and increases the viscosity of cervical mucus.

Specifications:
COA :


TEST ITEMS

SPECIFICATION

RESULTS

Description

White or Almost White Crystalline Powder

white powder

Identification

: A.B.

Positive

Assay

: 97.0~102.0%

99.3%

Specific Rotation

: +101°~+105°

+102.6°

Loss On Drying

: 1.0%max

0.27%

Melting Point

: 153~157°C

153.0~155.0°C

Organic Volatile Impurities

: meets the requirement.

Conforms

Related Substances

: meets the requirement.

Conforms

Residual Solvents

: meets the requirement.

Conforms

Particle Size

: 100% ≤ 20 microns

Conforms

Conclusion

The specification conform with USP30 standard


Our Service:
1.Fast Delivery:We can delivery within 24 hours upon receipt of your payment.
2.Quality can be promised.Hot sell to Worldwide.
3.Payment Terms:T/T,BITCOIN,MoneyGram,WESTERN UNION,Paypal Available.
4.Free Sample available at any time.
5.Tracking your order at any time.Inform your orders further new situation at any time.
6.Package:Professional packing with professional materials.

Our advantage:

1.We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2.Quality:Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries.We can provide good references about our company.As for the quality of the products, we e sure they can satisfy you well enough;
3.Package:Professional packing with professional materials
4.Delivery:We have products in stock, and we will deliver them soon when your PO arrived.Meanwhile we will give you the tracking number in order to make you know the exact location of the products.We will keep track of the product until they arrive you;We choose the best courier service for you, and with the delivery around 5-7 working days.
5.Service:Best Service with after-sales service and consultation

The main Product list

NO. Product Name CAS No.
1 Testosterone acetate CAS: 1045-69-8
2 Testosterone phenylpropionate CAS: 1255-49-8
3 CAS :58-22-0
4 Testosaterone decanoate CAS:5721-91-5
5 Testosterone cypionate CAS:58-20-8
6 Testosterone isocaproate CAS:15262-86-9
7 Testosterone enanthate CAS:315-37-7
8 Testosterone Undecanoate CAS:5949-44-0
9 Testosterone propionate CAS:57-85-2
10 CAS:434-22-0
11 Nandrolone Phenylpropionate CAS:62-90-8
12 Nandrolone Decanoate CAS:360-70-3
13 Trenbolone acetate CAS:10161-34-9
14 Trenbolone Hexahydrobenzyl Carbonate CAS:23454-33-3
15 Trenbolone enanthate CAS:472-61-546
16 Methenolone acetate CAS:434-05-9
17 Methenolone enanthate CAS:303-42-4
18 Articaine hydrochloride CAS:23964-57-0
19 Procaine hydrochloride CAS:51-05-8
20 Lidocaine Hydrochloride CAS:73-78-9
21 Propitocaine hydrochloride CAS:1786-81-8
22 Tetracaine hydrochloride CAS:136-47-0
23 Tamoxifen citrate CAS: 54965-24-1
24 Boldenone Acetate CAS:2363-59-9
25 Boldenone Cypionate CAS:106505-90-2
26 Boldenone Undecylenate CAS: 13103-34-9
27 CAS:846-48-0
28 Drostanolone Propionate CAS: 521-12-0
29 Drostanolone Enanthate CAS:472-61-145
30 CAS :2446-23-3
31 Sustanon 250
32 CAS:10418-03-8
34 Methyltrienolone CAS: 965-93-5
35 CAS: 1424-00-6
36 CAS : 58-18-4
37 Methandrostenolone CAS:72-63-9
38 Mebolazine CAS:3625-07-8
39 Medroxyprogesterone 17-acetate CAS:71-58-9
40 Methyltrienolone CAS:965-93-5
41 Diethylstilbestrol CAS: 6898-97-1
42 Dapoxetine CAS:119356-77-3
43 Drospirenone CAS:67392-87-4
44 CAS:17230-88-5
45 Dienogestrel CAS:65928-58-7
46 Nilestriol CAS: 39791-20-3
47 Nonoxynol CAS:26027-38-3
48 Estradiol valerate CAS: 979-32-8
49 Estradiol enanthate CAS: 4956-37-0
50 Ethisterone CAS:434-03-7
51 Ecdysone CAS:3604-87-3
52 Altrenogest CAS:850-52-2
53 CAS:645-05-6
54 Acetildenafil CAS:831217-01-7
55 CAS: 112809-51-5
56 Trilostane CAS:13647-35-3
57 CAS: 5630-53-5
58 Levonorgestrel CAS:797-63-7
59 Levobupivacaine hydrochloride CAS:27262-48-2
60 CAS:434-07-1
61 CAS:53-39-4
62 CAS:1239-29-8
63 CAS:76-43-7
64 Genistein CAS:446-72-0
65 CAS:52-01-7
66 Ropivacaine mesylate CAS:854056-07-8
67 CAS:171596-29-5
68 Benzocaine CAS:94-09-7
69 Yohimbine hydrochloride CAS:65-19-0
70 Lidocaine base CAS:137-58-6
71 CAS:224785-91-5
72 19-Norethindrone acetate CAS:51-98-9
73 Hydroxyprogesterone Caproate CAS:630-56-8
74 Pregnenolone CAS:145-13-1

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