Wuhan Hezhong Biochemical Manufacturing Co., Ltd.
Wuhan Hezhong Biochemical Manufacturing Co., Ltd.
Wuhan Hezhong Biochemical Manufacturing Co., Ltd. Quality first service-oriented!
  • Home
  • Product Categories
    • Drostanolone Propionate Masteron
    • Testosterone Anabolic Steroid
    • Muscle Growth Steroids
    • Oral Anabolic Steroids
    • Injectable Anabolic Steroids
    • Trenbolone Enanthate
    • Boldenone Steroid
    • Nandrolone Steroid
    • Anti Estrogen Steroids 
    • Raw Steroid Powders
    • Raw Hormone Powders
    • Male Enhancement Steroids
    • Growth Hormone Peptides
    • Pharmaceutical Intermediates
    • Chemical Food Additives
  • Company Profile
    • Company Introduction
    • Company News
  • Quality Control
  • Contact Us

Home>Products>Testosterone Anabolic Steroid>99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics

English
English
  • 99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics
  • 99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics
  • 99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics
  • 99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics

99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics

  • HZ
  • CAS 103-90-2

  • China
  • GMP, ISO 9001, USP, BP
  • 1g
  • Negotiable
  • as you required
  • 3-5 days
  • T/T, Western Union, Money Gram , Bitcoin
  • 1000kg/day
Contact NowChat Now
Wuhan Hezhong Biochemical Manufacturing Co., Ltd.

Wuhan Hezhong Biochemical Manufacturing Co., Ltd.China

  • Wuhan Hezhong Biochemical Manufacturing Co., Ltd.2020-07-10 09:46:19
    Welcome to my shop! Glad to serve you! Please send your question!
Price Inspection Certificate Product Specifications Company Profile

Product Details

Customized: Customized Suitable for: Adult Purity: 96%
Einecs: 211-351-6 HS Code: 29163920

Product Description

Basic Information

Chinese alias: acetaminophen, acetaminophen, paracetamol, fever net, acetaminophen, acetaminophen, cable secret, acetamidophenol, diacetylolol.

English name: 4-Acetamido phenol, paracetamol or acetaminophen.

English alias: Acetamino phen, 4-Hydroxyacetanilide, APAP, p-Hydroxyacetanilide, Paracetamol (Acetaminophen).

Quality standard: BP USP.

Content: 99% -101%.

CAS: 103-90-2.

Molecular formula: C8H9NO2.

Molecular weight: 151.16.

Physical and chemical properties: white crystalline powder, tasteless, soluble in hot water, ether, chloroform and so on.

Product use: antipyretic analgesics.

Packing: 25 kg per barrel (box) (woven bag).

The physical properties of this paragraph

Crystallization from the prism in ethanol. The temperature of 169-171 ° C, the relative density of 1.293 (21/4 ℃). Soluble in ethanol, acetone and hot water, insoluble in water, insoluble in petroleum ether and benzene. No smell, bitter taste. Saturated aqueous solution pH 5.5-6.5.

The preparation method of this paragraph

This product is derived from p-aminophenol acetylation.

Method 1: adding p-aminophenol to dilute acetic acid, adding acetic acid, heating to 150 ° C for 7 h, adding acetic anhydride, reacting for 2 h, checking the end point, passing and cooling to below 25 ° C, Sour, dried, crude.

Method 2: the p-aminophenol, glacial acetic acid and acid containing more than 50% acid distillation together, the rate of dilution of dilute acid per hour of the total amount of one-tenth of the total temperature to be above 130 ℃, Sampling Check the residual amount of p-aminophenol is less than 2.5%, add dilute acid (content of more than 50%), cooling crystallization. Filter, first with a small amount of dilute acid washing, and then a lot of water to the filtrate close to colorless, crude.

The yield of Method 1 was 90% and the yield of Method 2 was 90-95%.

Refining method: the water heated to near boiling when the crude product. Heat up to the whole solution, add water immersion activated carbon, with dilute acetic acid to adjust to pH = 4.2-4.6, boiling 10min. Pressure filtration, the filtrate plus a small amount of sodium sulfite. And cooled to 20 ° C or lower to precipitate crystals. Filter, washed, dried raw materials paracetamol finished products.

Other methods of production are: (1) reduction of p-nitrophenol with zinc in glacial acetic acid and acetylation to obtain acetaminophen; (2) hydrazone formed by p-hydroxyacetophenone in an acidic solution of sulfuric acid , Adding sodium nitrite, transposition to produce acetaminophen.

Folding pharmacology

Pharmacodynamics This product is acetanilide antipyretic analgesics. By inhibiting the cyclooxygenase, selective inhibition of hypothalamic body temperature regulation of the synthesis of central prostaglandins, leading to peripheral vascular dilatation, sweating and antipyretic effect, the antipyretic effect and aspirin similar; by inhibiting the synthesis of prostaglandins and other And release, improve the pain threshold and play a role in analgesic, are peripheral analgesics, the role of less than aspirin, only mild to moderate pain effective. This product has no obvious anti-inflammatory effect.

Pharmacokinetics after oral administration from the gastrointestinal tract quickly, completely (after high carbohydrate diet may reduce the absorption), absorbed in the body after the distribution of uniform, about 25% with the plasma protein binding. A small amount (blood concentration <60μg / ml) and protein binding is not obvious, a large number or a large amount of poisoning is a high rate of up to 43%. 90 ~ 95% of the goods in the liver metabolism, mainly with glucuronic acid, sulfuric acid and cysteine binding. The intermediate metabolites have toxic effects on the liver. Half-life β is generally 1 to 4 hours (2 hours on average), renal insufficiency, but in some patients with liver disease may be extended, the elderly and newborns may be extended, children are shortened. 0.5 to 2 hours after oral administration of plasma concentration up to the peak, the dose of 650mg or less when the plasma concentration of 5 ~ 20μg / ml, the duration of 3 to 4 hours. Lactation during the women taking the goods 650mg, 1 to 2 hours reported milk concentration of 10 ~ 15μg / ml; half-life β is 1.35 ~ 3.5 hours. The goods mainly with glucuronic acid in the form of excretion from the kidneys, about 24 hours within about 3% with the original shape with the urine.


Product Name 4-Acetamidophenol
Synonyms Paracetamol;4-ACETAMIDOPHENOL;4-ACETAMINOPHENOL;ACETAMINOPHEN
CAS 103-90-2
MF C8H9NO2
MW 151.16
EINECS 203-157-5
Product Categories PHARMACEUTICALS;Aromatic Phenols;Intermediates & Fine Chemicals;Lipid signaling;Aromatics;inhibitor;APIs
MP 168-172 °C(lit.)
Density 1,293 g/cm3
Fp 11 °C
Storage temp. Store at RT
Purity 99%
Chemical Properties White Solid
Usage Antiinfectant ,dispersing agent in liquid scintillation counting .Analgesic; antipyretic
Package 25kg/drum
Dispatch time Within 24h after confirming your payment
Leading time 4~6 working days after online
Delivery terms EMS , EUB , ETK , DHL , TNT , FEDEX , UPS , AIR , SEA
Payment terms WESTERN UNION , MONEYGRAM , T/T(BANK TRANSFER) , BITCOIN

Apply to relieve mild to moderate pain, such as colds caused by fever, headache, joint pain, neuralgia and migraine, dysmenorrhea and so on. The goods can only relieve symptoms, anti-inflammatory effect or minimal, can not eliminate arthritis caused by redness, swelling, activity disorders, it can not be used instead of aspirin or other non-steroidal anti-inflammatory drugs in the treatment of various types of arthritis. But the goods can be used for aspirin allergies, intolerance or unsuitable for the application of aspirin cases, such as chicken pox, hemophilia and other patients with hemorrhagic disease (including the application of anticoagulant therapy cases), and peptic ulcer, gastritis and so on. The use of the product when necessary, the need to apply other therapies at the same time to relieve pain or fever.

Use this amount

1. adult often used orally. A 0.3-0.6g, every 4 hours 1, or 4 times a day; day should not exceed 2g, treatment for fever generally no more than 3 days, for the analgesic should not exceed 10 days.

2. children often use oral. According to the weight of each 10-15mg / kg or body surface area of 1.5g / square meter per day, sub-service, every 4-6 hours 1; children under 12 years of age every 24 hours no more than 5 times the amount of treatment does not exceed 5 days The

Collapse Edit this paragraph toxic side effects

White plus black, Parco, Tylenol cold tablets, cold spirit, to pain tablets, etc. contain paracetamol, the dose of about 120-500 mg range. But the wide range of clinical applications, there have been some side effects, to cause everyones vigilance.

1, the liver side effects: long-term or excessive use can cause liver cell necrosis. Paracetamol caused by liver cell necrosis is its direct role on the liver cells may be excessive use of paracetamol caused by the body to produce a toxic metabolite, when the accumulation reaches a certain amount, resulting in depletion of liver glutathione, the liver detoxification capacity greatly reduced, Toxic metabolites destroy liver cells, producing cell degeneration and necrosis. Due to excessive paracetamol caused by acute hepatic lobular central necrosis, rapid progress can occur in fulminant liver failure and cause death.

2, the kidney side effects: excessive paracetamol produced by the toxic metabolites can also damage the kidneys, resulting in renal cell necrosis, especially in combination with sodium salicylate or caffeine, more easily damage the kidneys.

3, the blood system toxicity: long-term excessive paracetamol, the resulting toxic metabolic products can be directly on the role of bone marrow hematopoietic system, constitute damage, may also induce thrombocytopenic purpura or leukemia.

4, the nervous system side effects: If the child taking acetaminophen, can also cause symptoms of central nervous system poisoning, mainly brain damage, neurological dysfunction, into a coma and so on.

Rare, such as the occurrence of allergic reactions should be immediately stopped taking.

Note this paragraph

· Excessive administration Please consult your doctor immediately.

• Do not take other medications with acetaminophen.

· If you have severe sore throat, accompanied by fever, headache skin treatment of nausea or vomiting, should seek medical treatment.

· Avoid drinking alcoholic beverages during the medication, drinking the patient should be under the guidance of the doctor taking the goods and other painkillers.

In the following cases taking acetaminophen can cause liver damage

(1) excessive use.

(2) long-term high-dose taking.

(3) drinking or drinking alcoholic beverages.

(4) liver disease patients taking small doses can also damage the liver.

(5) mix it with other headaches containing paracetamol, cold medicine and other drugs. US researchers survey of 300 patients with severe liver failure showed that 38% of the cases were associated with taking acetaminophen. In another group of 307 adults with severe liver damage, 35% of the cases were found to be associated with paracetamol. In these cases, most of them are accidents, due to lack of attention.

Related drugs recommended

Our advantage

1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we e sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation


China Customized Inflatable Bumper Ball Game Bubble Adult Grass CE supplier

99% Purity Paracetamol 4-Acetamidophenol CAS 103-90-2 Antipyretic Analgesics Images

Contact Us

Wuhan Hezhong Biochemical Manufacturing Co., Ltd.
Address
Phone(Working Time)
Fax
  • Wuhan Hezhong Biochemical Manufacturing Co., Ltd.
    • Quick question Quick question I'm very interested in your products; could you send me some detail reference information? Please send me detail product specification, thank you! May I be an agency of your products,and what's yourterms? We intend to purchase this product, would you please send me the quotation and minimum order quantity?
    What is this?This feature is Quick question function, select the corresponding question types, automatically enter the corresponding problem, remove your trouble of typing
Send Now

Product Categories

  • Drostanolone Propionate Masteron
  • Testosterone Anabolic Steroid
  • Muscle Growth Steroids
  • Oral Anabolic Steroids
  • Injectable Anabolic Steroids
  • Trenbolone Enanthate
  • Boldenone Steroid
  • Nandrolone Steroid
  • Anti Estrogen Steroids 
  • Raw Steroid Powders
  • Raw Hormone Powders
  • Male Enhancement Steroids
  • Growth Hormone Peptides
  • Pharmaceutical Intermediates
  • Chemical Food Additives
More

New Products

  • Testosterone Anabolic Steroid Powder Trenbolone Acetate/Tren Ace/Tren Acetate
  • Oral Anabolic Steroids L-Thyroxine T4 51-48-9 in White Powder ISO 9001
  • Human Growth Hormone Peptides Testosterone Anabolic Steroid PEG MGF Supplements
  • CAS 5086-74-8 Testosterone Anabolic Steroid Tetramisole Hydrochloride
  • CAS 58-22-0 Testoviron Raw Testosterone Powder Virilon Steroids For Breast
Tags:

tags1:Raw Testosterone Powder

legal testosterone steroids

  • About Us|
  • Contact Us|
  • Site Map

Wuhan Hezhong Biochemical Manufacturing Co., Ltd.. Copyright © 2017 - 2021 All Rights Reserved.

  • Home
  • Product Categories
    • Drostanolone Propionate Masteron
    • Testosterone Anabolic Steroid
    • Muscle Growth Steroids
    • Oral Anabolic Steroids
    • Injectable Anabolic Steroids
    • Trenbolone Enanthate
    • Boldenone Steroid
    • Nandrolone Steroid
    • Anti Estrogen Steroids 
    • Raw Steroid Powders
    • Raw Hormone Powders
    • Male Enhancement Steroids
    • Growth Hormone Peptides
    • Pharmaceutical Intermediates
    • Chemical Food Additives
  • Company Profile
    • Company Introduction
    • Company News
  • Quality Control
  • Contact Us